New Opioid Receptor Modulators and Agonists

Relevance for Pain and Opioid Use Disorder Management
Autor: Kaye Alan David (Hrsg.)
CHF 215.00
ISBN: 978-0-443-26504-4
Einband: Kartonierter Einband (Kt)
Verfügbarkeit: Noch nicht erschienen, Oktober 2025
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New Opioid Receptor Modulators and Agonists: Relevance for Pain and Opioid Use Disorder Management provides crucial insights for developing ideal synthetic opioids. It discusses opioid receptor modulators’ structures and mechanisms, and their potential applications in treating pain, misuse, and addiction. This comprehensive resource delves into current research and therapeutic development avenues regarding opioid receptors' structure and function. Sections cover the rationale for developing allosteric modulators, identifying allosteric sites on opioid receptors, and the modulators' modes of action. Readers will gain a thorough understanding of creating ideal synthetic opioids and potential future research.

It also explores pharmacogenomics, precision medicine, and various syndromes and comorbidities linked to opioid use. Lastly, it reviews novel synthetic opioids and the risks of misuse and overdose.

New Opioid Receptor Modulators and Agonists: Relevance for Pain and Opioid Use Disorder Management provides crucial insights for developing ideal synthetic opioids. It discusses opioid receptor modulators’ structures and mechanisms, and their potential applications in treating pain, misuse, and addiction. This comprehensive resource delves into current research and therapeutic development avenues regarding opioid receptors' structure and function. Sections cover the rationale for developing allosteric modulators, identifying allosteric sites on opioid receptors, and the modulators' modes of action. Readers will gain a thorough understanding of creating ideal synthetic opioids and potential future research.

It also explores pharmacogenomics, precision medicine, and various syndromes and comorbidities linked to opioid use. Lastly, it reviews novel synthetic opioids and the risks of misuse and overdose.

Autor Kaye Alan David (Hrsg.)
Verlag Elsevier
Einband Nonbook (Non)
Erscheinungsjahr 2025
Ausgabekennzeichen Englisch
Masse H27.6 cm x B21.6 cm 450 g
Coverlag Academic Press Inc (Imprint/Brand)

Über den Autor Kaye Alan David (Hrsg.)

Alan David Kaye, a Rhodes Scholar state selection and national runner-up as an undergraduate, completed two B.S. degrees, one in Psychology and one in Biology, and his medical degree from the University of Arizona, School of Medicine, along with a Ph.D. in Pharmacology from the Tulane School of Medicine in 1997. He did his residency training at Harvard University's Massachusetts General Hospital and at Tulane Medical Center, along with a fellowship in Pain Management at Texas Tech Medical School, in Lubbock. He is triple board certified and for six years (1999-2005), he served as Chairman and Professor of the Department of Anesthesiology at Texas Tech Medical Health Sciences Center and Professor of Pharmacology at Texas Tech Medical Center. In 2005, he became Chairman and Professor of the Department of Anesthesiology, Director of Interventional Pain Medicine, and Professor of Pharmacology at the LSU School of Medicine in New Orleans. He is one of the most prolific publishers in the field of anesthesiology worldwide, is a noted book editor and national/international lecturer, is a member of the Anesthesia and Analgesics section of the Food and Drug Administration (FDA), and is the editor-in-chief of the highly regarded journal Pain Physician.Richard D. Urman is an anesthesiologist at the Brigham and Women's Hospital (BWH) in Boston and Associate Professor of Anesthesia at Harvard Medical School. He serves as Chief of Anesthesia Services at the BWH Care Center at Chestnut Hill, and as Medical Director of Sedation for Interventional Medicine, where his responsibilities include overseeing all hospital procedural sedation areas (adults and neonates), quality assurance, education and credentialing programs. He also serves as the Director (Anesthesia) of the interdepartmental Center for Perioperative Research at BWH and directs the newly established Perioperative Medicine Fellowship. Dr Urman received his M.D. from Harvard Medical School, M.B.A. from Harvard Business School, and completed a residency in anesthesia at BIDMC/Harvard Medical School. He is a Certified Physician Executive (from AAPL). Dr Urman's specialty interests include perioperative medicine and preoperative assessment, general and regional anesthesia, sedation/anesthesia outside of the operating room, and acute pain management. His research areas encompass patient outcomes, informatics, patient safety, novel anesthetic drugs, simulation, and operating room management. He has published over 250 peer-reviewed papers, book chapters and also edited over 10 books.Charles J. Fox, III is an anesthesiologist at Louisiana State University Health in Shreveport. He serves as the Professor and Chair of the Department of Anesthesiology and President and CEO of the LSUHSC Faculty Group Practice Plan. He received his M.D. from Louisiana State University Health in New Orleans and completed his anesthesiology residency training at Yale New Haven Hospital and pediatric cardiac anesthesiology fellowship at The Children's Hospital of Philadelphia. He helped establish the Tulane Department of Anesthesiology Perioperative Management Fellowship. He has published over 100 peer-reviewed papers, book chapters and also edited over 4 books.

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